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KMID : 0812020070130020132
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Korean Journal of Neurogastroenterology and Motility
2007 Volume.13 No. 2 p.132 ~ p.137
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Rectal Accommodation in Irritable Bowel Syndrome
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Moon Won
Lee Oh-Young
Kim Jung-Mi
Koh Dong-Hee
Lee Hang-Lak
Yoon Byung-Chul
Choi Ho-Soon
Hahm Joon-Soo
Lee Min-Ho
Lee Dong-Hoo
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Abstract
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Background/Aims: Visceral hypersensitivity has been proposed as a biologic marker of irritable bowel syndrome (IBS). Several studies have demonstrated that patients with IBS have lower threshold for perception and increased sensation of discomfort. Our aim was to investigate if IBS patients have different rectal accommodation compared with normal controls or if the differences exist in rectal accommodation according to the IBS subtypes.
Methods: Twenty three Rome II positive IBS patients and 9 normal controls were recruited for the study. A rectal bag catheter was placed, and then bag inflation was performed via a barostat.
Results: There were no differences in rectal accommodation between IBS patients (1.1 mL/s) and the normal controls (1.4 mL/s). But, there were significant differences in rectal accommodation between diarrhea predominant IBS patients (1.0 mL/s) and the normal controls (1.4 mL/s) (p=0.05). There was no correlation between rectal accommodation and the severity of overall gastrointestinal symptoms, but the severity of abdominal discomfort or pain during rectal distension tended to be associated with rectal accommodation (p=0.08).
Conclusions: There were no differences between IBS patients and normal controls in rectal accommodation. But, lowered rectal accommodation was significant in diarrhea predominant-IBS patinets. (Kor J Neurogastroenterol Motil 2007;13:132-137)
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KEYWORD
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Irritable bowel syndrome, Rectal accommodation, Subtypes
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